What to watch: Santana still rolling

For the fifth time this season, the Indians have a losing streak of four games or more as they get set to face Arizona Wednesday night.

Cleveland Indians' Carlos Santana runs the bases after hitting a two-run home run.

Matt York / AP

For the fifth time this season, the Indians have a losing streak of four games or more as they get set to face Arizona Wednesday night.

The Tribe lost their fourth straight early Wednesday morning after the Diamondbacks rallied for a 9-8 lead in 14 innings. It marked the third game this year that the Indians have played that lasted 12 innings or more.

Since late April, "team streak" has gone to extremes. After dropping six straight on the west coast to end April, the Indians opened May by winning eight of their first 12. After then dropping their next four, the Indians won five of six. Then came a four-game skid followed by wins in nine of the next 10 from May 30-June 9.

Cleveland then was swept in a two-game series at Kansas City and the first two at Boston before taking four of five. And now there's another four-game losing streak.

Here's what to watch for during Indians Live pregame and during the game:

Santana still rolling: Carlos Santana reached base in his first six plate appearances on Tuesday and was 4 for 5 with a home run and two RBI. He is batting .371 in June with six home runs and 14 RBI along with raising his batting average 55 points (from .159 to .214) since coming off the disabled list.

Axford's struggles: You have to wonder how much longer Terry Francona can remain patient with John Axford. In his past six appearances, the right-hander has allowed four runs, six hits and seven walks in 4 2/3 innings. In a high-leverage situation on Tuesday, he allowed the game-tying hit.

Kluber looks for first June win: After going 4-0 in six May starts, Corey Kluber is 0-2 with a 4.18 ERA in four games this month. Kluber (6-5, 3.30) Kluber is 5-0 with a 2.78 ERA in five Interleague starts.

Kluber vs. Diamondbacks: Corey Ross 0-2.

Diamondbacks starter: Chase Anderson (5-2, 3.18) has won three of his last four home starts. He won his first five starts, becoming only the third pitcher since 1998 to do that, joining Jered Weaver (seven in 2006) and Kazuhisa Ishii (six in 2002).

On the run: The Diamondbacks have eight straight successful stolen base attempts and 18 of the last 19.

Breaking a slump: Gerardo Parra, who was 4 for 33 in his last eight games coming into Tuesday, tied a career high with five hits.