Mike Fisher and Gabriel Bourque scored for Nashville, which won its second straight and improved to 3-1 against Chicago this season.
The Blackhawks outshot the Predators 29-17 and generated ample chances despite playing their second game without Patrick Kane, the team's leading scorer when he was injured against St. Louis on Wednesday. The star forward is on injured reserve with a lower-body injury and could miss the rest of the regular season.
Chicago fell six points behind Western Conference and Central Division leader St. Louis, which defeated Pittsburgh 1-0 earlier on Sunday.
Fleury made 26 saves for the Penguins but watched Backes' deflection carom off his glove and into the net just after a penalty against Malkin expired.
St. Louis bounced back from a one-sided loss at Philadelphia on Saturday to improve the league's best road record to 23-11-3. Pittsburgh's top-ranked power play went 0-for-5 a day after scoring three times in a win over Tampa Bay.
UNIONDALE, N.Y. (AP) - Evgeni Nabokov made 41 saves in his 58th NHL shutout, and Travis Hamonic scored a coast-to-coast, power-play goal in the second period and New York dealt the Blue Jackets' playoff hopes a severe blow.
Nabokov got the best of Russian counterpart Sergei Bobrovsky in their third meeting this season and posted his third shutout in this campaign. It was just the Islanders' second regulation win ever over the Blue Jackets.
Columbus, which has dropped to fifth in the Metropolitan Division, has fallen out of an Eastern Conference playoff position with 11 games left. The Blue Jackets lost their second straight game and for the third time in four. This one was particularly costly as the Islanders are far out of postseason contention.
Cal Clutterbuck also scored for the Islanders, who bounced back from a 6-0 loss to Minnesota on Tuesday and finished a 2-2 homestand.
The Canucks have consecutive wins for the first time since mid-January. Vancouver pulled within three points of eighth-place Phoenix, and one point of ninth-place Dallas in the race for the second wild-card playoff spot in the Western Conference.
The Sabres, last in the NHL by a wide margin, suffered their eighth loss in the past 10 games as they squandered an early 2-0 lead.