The injury seriously hinders Nashville's plans to boost its offense under new coach Peter Laviolette.
After missing the playoffs for a second straight season, Poile fired coach Barry Trotz and replaced him with Laviolette, emphasizing the need to add more scoring punch to a franchise that traditionally has prided itself on defense.
The Predators have spent much of the offseason attempting to boost that offense. They acquired forward James Neal from the Pittsburgh Penguins and signed free-agent center Olli Jokinen to a one-year, $2.5 million contract.
But the Predators would suffer a major blow if they have to spend much of the season without Fisher, one of the team's top offensive threats since coming to Nashville in a 2011 trade with the Ottawa Senators.
Monday's news continues the Predators' recent run of bad luck with injuries to key players. Star goaltender Pekka Rinne played only 24 games last season because of an E. coli infection in his surgically repaired left hip. Rinne's injury may have cost the Predators a playoff berth, as they finished the season three points out of eighth place in the Western Conference.