San Francisco LB Willis out against Cardinals
GLENDALE, Ariz. (AP)
He sat out the regular season finale in 2010 with a broken hand.
Willis, who did some stretching before Sunday's game, did not practice all last week because of a right hamstring injury. He was replaced in the lineup by Larry Grant.
49ers wide receiver Braylon Edwards was active after missing last week's NFC West-clinching victory over St. Louis with a sore right knee.
Arizona had three wide receivers inactive as coach Ken Whisenhunt chose to dress all four of his tight ends.