It's true that Luck was limited to just seven games due to injuries last season, but the Colts were just 2-5 in those contests, and Luck racked up an alarming 12 INTs. We've seen him be much better than that, and after the Colts gave him a huge new contract this summer, there's plenty of incentive for Luck to return to the form that helped lead Indy to the playoffs in each of his first three seasons.
Getty ImagesAndy Lyons
DeSean Jackson, Washington Redskins
The Redskins finished 9-7 and first in their division last season, and did so largely without the help of their best wide receiver. Jackson finished with just 30 catches for 528 yards in 10 games, one season removed from leading the team in receiving yards (1,169) and the league in yards per catch (20.9).
Getty ImagesPatrick Smith
Eddie Lacy, Green Bay Packers
Lacy's production dropped significantly, from more than 1,100 rushing yards in each of his first two seasons to 758 yards last year, and there's no question that the Packers offense struggled because of it. After an offseason fitness program that has him feeling more explosive than ever, Lacy should be ready for big things in 2016.
Getty ImagesJoe Robbins
Dez Bryant, Dallas Cowboys
Bryant was plagued by a foot injury last season, and that (along with Tony Romo playing in just four games due to injury) was enough to result in statistics that were the worst in the two-time Pro Bowler's six-year career. With Romo and Dez both healthy entering 2016, Bryant should have no trouble playing like the guy who hauled in a league-leading 16 TDs in 2014.
Jimmy Graham, Seattle Seahawks
Graham never will be the focal point of the passing attack in Seattle the way he was in his five seasons in New Orleans, but he needs to find a way to get on the same page with Russell Wilson and be a productive member of the offense. He's the NFL's highest-paid tight end, so two touchdowns in 11 games last season really are not enough for the team to justify the expense.
Getty ImagesOtto Greule Jr
DeMarco Murray, Tennessee Titans
Murray was an absolute beast with the Cowboys in 2014, leading the league in rushing with 1,845 yards and 13 TDs. But he took a significant step back in Philadelphia last season, and now finds himself in Tennessee battling for the starting job. It's tough to read too much into the preseason, but Murray racked up 93 yards on just six carries in Tennessee's first game, including a 71-yard run for a touchdown.
Getty ImagesFrederick Breedon
Joe Flacco, Baltimore Ravens
Forget the question of whether or not Flacco is elite. In 2016, it's about whether or not he can be serviceable. The Ravens were just 3-7 in Flacco's 10 games last season, and his 14-12 TD-to-INT ratio didn't exactly inspire confidence.