MAY 14, 2014 2:05a ET
The Arizona Diamondbacks will try to continue their recent turnaround by winning their first home series of the season. They'll also look to extend Doug Fister's rough return from the disabled list for the Washington Nationals.
The Diamondbacks, though, will have a struggling right-hander of their own starting Wednesday's finale in Brandon McCarthy.
Arizona has won eight of its last 12 to match its victory total from its first 30 games this season. The Diamondbacks (16-26) fell 6-5 in Monday's opener with the Nationals after giving up two runs in the ninth but bounced back with a 3-1 victory Tuesday, improving to 4-16 at home.
Bronson Arroyo outdueled Stephen Strasburg, and Paul Goldschmidt hit a go-ahead double in the fifth. The Nationals had won six of eight in Arizona and nine of 12 overall in the series before Tuesday's defeat.
"You just want to get it done at home to show there's not some sort of jinx going on," Arroyo said.
Arizona will try to close out the three-game set by sending Washington (20-19) to its eighth loss in 11 games. A matchup with Fister (0-1, 10.38 ERA) might help if his first start for the Nationals was any indication.
Fister was tagged for seven runs and nine hits, including three homers, in 4 1-3 innings Friday in an 8-0 loss to Oakland. The right-hander, acquired from Detroit in the offseason, strained his right lat in spring training.
"Physically, I felt like I was in the right place. I felt strong. It was lack of execution," Fister said. "It's a matter of going out and executing, whether you are sore or feeling good. You have to make the adjustments, and I didn't do that."
In his first start against Arizona, Fister will try to send McCarthy (1-6, 5.66) to another loss. The Arizona right-hander couldn't make it out of the fourth inning Friday against one of his former teams, the Chicago White Sox, and was charged with a season-high seven runs in a 9-3 loss.
"Everything felt the exact same as the first three innings. Just all of a sudden, every pitch I threw, I was turning and watching it go somewhere else. I'm baffled at this point," he said.
McCarthy had given up a combined three earned runs over 19 innings in his three previous starts, and he pitched seven scoreless May 3 in a 4-3 win in San Diego.
McCarthy was on the wrong end of a 2-0 score in his only start against Washington on Sept. 28, yielding two runs and five hits over seven innings.
Eric Chavez is 3 for 11 in his career against Fister. The other three active Diamondbacks players to have faced the right-hander - Cliff Pennington, Aaron Hill and Cody Ross - are a combined 2 for 29, with Pennington going 1 for 21.
Denard Span is 4 for 12 lifetime against McCarthy, but the rest of his teammates have combined for one hit in 20 at-bats.