The Diamondbacks look to do both while trying to match a season high with their fifth consecutive victory and hand the Reds a fourth straight defeat Sunday.
One night after Arizona (41-33) pounded out 15 hits in an 11-5 win over Cincinnati, Jason Kubel delivered a two-run single off Aroldis Chapman in the bottom of the ninth inning for 4-3 comeback victory Saturday.
Cincinnati's Mike Leake and Arizona's Patrick Corbin engaged in a pitchers' duel before Gerardo Parra gave the Diamondbacks a 2-1 lead with a two-run homer in sixth. Jay Bruce tied it in the ninth with his second home run of the game before the hosts prevailed.
The Reds (44-32) had won three straight and 12 of 14 at Arizona prior to this series, but are now in danger of being swept there for the first time since June 20-22, 2003.
"It's a tough one to swallow but we will be right back there (Sunday)," said Leake, who allowed two runs and four hits in eight innings.
Cincinnati should feel confident behind Latos (6-1, 3.20 ERA), who is 2-0 with a 1.73 ERA in four starts at Chase Field.
The right-hander was 10-0 with a 2.80 ERA in 21 regular season starts before he allowed three runs in the first and three hits over five innings while striking out nine in a 4-0 loss to Pittsburgh on Tuesday.
"I was aggravated with myself,'' Latos said. "I didn't throw too well in the bullpen and kind of took it into the first. I beat myself (Tuesday). It's always hard when you put your team in a 3-0 hole.''
Cincinnati's defeat Saturday overshadowed Bruce's continued power display.
The right-fielder drove in all three runs and matched a career high by homering in his fourth consecutive game. All seven of Bruce's hits in his last 29 at-bats have been home runs.
He is 3 for 8 in the series after going 0 for 19 in his previous five games versus Arizona.
Parra has homered in back-to-back games for the first time in his career, and is batting .356 with seven RBIs in his last 15 overall.
He's 4 for 12 against Latos.
Randall Delgado (0-0, 4.00) gets a second straight start Sunday since he was recalled from the minors this week. Arizona manager Kirk Gibson has decided to go with a four-man rotation with Brandon McCarthy injured and Ian Kennedy in the midst of a 10-game suspension.
Delgado gave up two runs and struck out six without a walk in seven innings of a 3-2 win over Miami on Tuesday.
"When he came up and threw (earlier this month) he wasn't as aggressive as he could be,'' Gibson said. "But you could see he shortened his motion and focused on locating the ball more. I think in spring training we were looking at a guy who was more of a thrower.''
The right-hander went 0-1 with a 3.00 ERA in two starts against the Reds while pitching for Atlanta last season.