"I breezed this filly Saturday, and when I pulled her up I started crying because I couldn't believe I had another Queen's Plate winner," Husbands said. "On the way back to the barn I told the assistant, `Could you tell Mark `I don't think they will beat this filly.' "
Lexie Lou paid $8.20 to win.
Asserting Bear was third in the 15-horse field.
The victory was the fifth in 12 career starts for Lexie Lou, with the $600,000 winner's share boosting her earnings past $1.2 million.
The second leg of the Canadian Triple Crown is the Prince of Wales Stakes on July 29 at Fort Erie.