Acosta hits hat-trick against Pumas
Queretaro remain without a win in the Mexican Apertura after losing 2-1 at home to Morelia on Saturday.
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Substitute Joao Rojas put the visitors in front on 52 minutes and although Diego Vera equalised soon after, Miguel Sabah scored a 90th-minute winner before promptly getting sent off.
Queretaro have taken just three points from 14 games this season and are eight points behind second-bottom Atlas, who lost at home to San Luis.
Hector Mancilla (24) opened the scoring for Atlas, but San Luis hit back through Emmanuel Cerda (46) and an own goal from Facundo Erpen.
Erpen made amends by scoring at the right end on 65 minutes, but Santiago Trellez (82) scored the winner just three minutes after coming off the bench.
Elsewhere, Club America came from behind to beat Leon 2-1, with the visitors taking the lead through Nelson Maz just two minutes into the second half.
Christian Bermudez equalised on 71 minutes and Christian Benitez then grabbed the winner four minutes from time.
Tigres enjoyed a comprehensive 5-0 win over Unam Pumas, with the first three goals coming in a six-minute spell.
An own goal from Marco Palacios (20) opened the floodgates and Alberto Acosta scored seconds later before adding another on 27 minutes.
Acosta completed his hat-trick on the hour mark and Elias Hernandez (82) rounded off the rout.
In the day's final game, Pachuca and Monterrey drew 1-1 with Angel Reyna opening the scoring after just two minutes for Monterrey, but Felix Borja equalising early in the second half for the home side.