PSV scores six in impressive victory
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The Boeren were thoroughly rampant at the Kyocera Stadion, splitting their goals equally before and after the break as Maurice Steijn's men were overrun.
The six-goal success comes at the end of a week which has seen PSV manager Dick Advocaat linked with a surprise move to England, but any thoughts of such a switch will surely have been quashed as his men underlined their title credentials.
Luciano Narsingh got them going in the 14th minute and with Kevin Strootman (23) and Dries Mertens (33) also on target, the game was over as a contest by half-time.
PSV continued to excel after the break too, Georgino Wijnaldum making it four ahead of Charlton Vicento's consolation.
Even then there was time for more goals, with Timothy Derijck and substitute Orlando Engelaar putting the seal on things for the visitors.
PSV are nine points clear of defending champions Ajax, who at least won ahead of a vital week of Champions League fixtures.
They were 2-0 victors over second bottom VVV Venlo, who hung in the contest until Dirk Boerrigter put them ahead in the 47th minute. Substitute Danny Hoesen wrapped things up with six minutes left.
Their hero was Florian Jozefzoon, with the rising star scoring twice, first in the seventh minute and secondly on the hour as he took his seasonal tally to four.
Tim Sparv drew first blood for Groningen, but the Pride of the North were unable to see the job through, with Holland international Adam Maher levelling 19 minutes from time.
Half-time substitute Ronnie Reniers (69) broke the deadlock and Denni Avdic wrapped things up with 11 minutes left.